Table of Contents
Main Page
enviPath is an online, publically available database and prediction system for microbially mediated biotransformations of organic environmental contaminants. It is the successor of the University of Minnesota Biocatalysis/Biodegradation Database and Pathway Prediction System (UM-BBD/PPS) and is a continually evolving product of over 20 years of international scientific collaboration. The enviPath platform provides a thorough, mechanistic understanding and prediction of biotransformation pathways and rates in different experimental and environmental conditions such that academic research teams, consultants, public authorities, and chemical industries can collectively work to reduce harmful chemical contamination in the environment.
Database
The enviPath database stores reviewed pathways from the scientific literature and predicted or user-entered pathways. You can browse information in the database using the menu on the top banner of start page. The database is organized in packages. Each package has an owner who can grant reading or writing permissions. We list data only as reviewed if it is reviewed by one of the organisations or groups in the reviewer group.
Prediction
enviPath can be used to predict biotransformation pathways. You can do this by simply using the input field on the start page. Enter a compound in SMILES format, or draw it using the molecule editor (by clicking on the dropdown on the left), and click on “Go!”. If the pathway for this compound was predicted before and is found in the database, a list of corresponding pathways will be returned. Otherwise, the system will predict the pathway. Note that for anonymous users there is a limit to computation time and size of the predicted pathways. The resulting pathway will be stored in the database for 30 days and will be accessible and changeable for everyone. If you want to store the pathway for longer, prevent others from changing or seeing your pathways, or use more resources in terms of computation time and size of pathways, create an account (using the login button above) and set appropriate permissions for your data packages (the default settings should be suitable for most users).
Cite
Cite enviPath using
enviPath–The environmental contaminant biotransformation pathway resource. J Wicker, T Lorsbach, M Gütlein, E Schmid, D Latino, S Kramer, K Fenner. Nucleic Acids Research, gkv1229 (full text)