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enviPath is an online, publically available database and prediction system for microbially mediated biotransformations of organic environmental contaminants. It is the successor of the University of Minnesota Biocatalysis/Biodegradation Database and Pathway Prediction System (now EAWAG-BBD/PPS) and is a continually evolving product of over 20 years of international scientific collaboration. The enviPath platform provides a thorough, mechanistic understanding and prediction of biotransformation pathways and rates in different experimental and environmental conditions such that academic research teams, consultants, public authorities, and chemical industries can collectively work to reduce harmful chemical contamination in the environment.


The enviPath database stores reviewed pathways from scientific literature and predicted or user-entered pathways. You can browse information in the database using the menu on the top banner of start page. The database is organized in packages. Each package has an owner who can grant reading or writing permissions. We list data only as reviewed if it is reviewed by one of the organisations or groups in the reviewer group.


enviPath can be used to predict biotransformation pathways. You can do this using the input field on the start page by entering a compound in SMILES format, or drawing it using the molecule editor (by clicking on the dropdown on the left), and clicking “Go!”. If the pathway for this compound was has been previously predicted and it is found in the database, a list of corresponding pathways will be returned. Otherwise, the system will generate a new predicted pathway. Note that for anonymous users there is a limit to computation time and size of the predicted pathways. The resulting pathway will be stored in the database for at least 30 days and will be accessible to everyone. Data generated by anonymous users is at risk of getting deleted after 30 days. If you wish to store the pathway for longer, prevent others from changing or seeing your pathways, or use more resources in terms of computation time and size of pathways, please create an account (using the login button) and set appropriate permissions for your packages (default settings should be suitable for most users).


Cite enviPath using

enviPath–The environmental contaminant biotransformation pathway resource. J Wicker, T Lorsbach, M Gütlein, E Schmid, D Latino, S Kramer, K Fenner. Nucleic Acids Research, gkv1229 (full text)




start.txt · Last modified: 2024/04/16 12:21 by strich